I've got chance to try Distant worlds myself. As Kordanor said, it's not for everyone.
Critics first: >4GB memory or prepare for constant crashes. Interface and graphics are very... uncommon. Some design desicions are questionable.
But then you realize you've been playing for 5 hours straight, ships are many, managers are helpful, and graphics aren't that bad especially when you are dealing with battles.
It's a large scale 4X, when you'll spend much more on the economy planning, strategical decisions and global oversight than micromanaging every ship in every battle. There are lot of interesting choices to do, but rather than "What cannons should this ship have" it's "Where i should build deep space scanning station to spy for one empire and avoid provoking the other" kind of choices.
I haven't seen a global 4X game more detailed and thought-through. Still it'd be great to try before buying.
Also, Dix, if the weird graphics don't bother you, i'd highly recommend AI War from Arcen Games. Very interesting idea, progressive difficulty, challenging gameplay, nice balance and lots of things to discover.